Eloxx Pharmaceuticals, Inc.
480 Arsenal Way

Watertown, MA 02472

 

August 26, 2021

 

Via EDGAR Transmission

Securities and Exchange Commission

Division of Corporation Finance

Mail Stop 4720

100 F Street, N.E.

Washington, D.C. 20549

 

Re:ELOXX PHARMACEUTICALS, INC.

 

Registration Statement on Form S-3 (Registration No. 333-258994)

 

Ladies and Gentlemen:

 

In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-3 (Registration No. 333-258994) (the “Registration Statement”) of Eloxx Pharmaceuticals, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:30 p.m., Eastern Time, on August 30, 2021, or at such later time as the Company or its counsel may orally request via telephone call to the staff. Please contact Wesley C. Holmes of Latham & Watkins LLP, counsel to the Company, at (617) 948-6027, or in his absence, Peter Handrinos at (617) 948-6060, to provide notice of effectiveness, or if you have any other questions or concerns regarding this matter.

 

  Very truly yours,
   
  ELOXX PHARMACEUTICALS, INC.
   
   
  By: /s/ Sumit Aggarwal
    Name: Sumit Aggarwal
    Title: Chief Executive Officer

 

cc: Daniel E. Geffken, Eloxx Pharmaceuticals, Inc.
  Peter N. Handrinos, Latham & Watkins LLP
  Wesley C. Holmes, Latham & Watkins LLP